Synergistic Antibacterial Activity of an Active Compound Derived from <i>Sedum takesimense</i> against Methicillin-Resistant <i>Staphylococcus aureus</i> and Its Clinical Isolates
Eun-Tak Jeong, Seulki Park, Du‐Min Jo, Fazlurrahman Khan, Tae Ho Choi, Tae-Mi Yoon, Young‐Mog Kim
Abstract
, oxacillin) demonstrated synergistic action against MRSA, with a fractional inhibitory concentration (FIC) index of 0.281. The current research revealed an alternative approach to combating pathogenesis caused by multi-drug resistant bacteria using plant materials. Furthermore, using a combination approach in which the active plant-derived compound is combined with antibiotics has proved to be a successful way of destroying pathogens synergistically.
Topics & Concepts
Pathogenic bacteriaAntimicrobialMicrobiologyStaphylococcus aureusBacteriaAntibioticsAntibacterial activityMinimum inhibitory concentrationBiologyGeneticsAntimicrobial Resistance in StaphylococcusEssential Oils and Antimicrobial ActivityAntibiotic Resistance in Bacteria