Conserved class B GPCR activation by a biased intracellular agonist
Lihua Zhao, He Qian, Qingning Yuan, Yimin Gu, Xinheng He, Hong Shan, Junrui Li, Kai Wang, Yang Li, Wen Hu, Kaichun Wu, Jianhua Shen, H. Eric Xu
Topics & Concepts
G protein-coupled receptorRhodopsin-like receptorsReceptorAgonistArrestinG proteinSmall moleculeBinding siteBiochemistryChemistryBiologyClass C GPCRCell biologyMetabotropic glutamate receptorMetabotropic receptorReceptor Mechanisms and SignalingDiabetes Treatment and ManagementProtein Kinase Regulation and GTPase Signaling