Intracellular trafficking of silver nanoparticles and silver ions determined their specific mitotoxicity to the zebrafish cell line
Neng Yan, Ben Zhong Tang, Wen‐Xiong Wang
Abstract
AgNP toxicity was attributed to dissolved Ag<sup>+</sup>, which was released, transported, and concentrated in the mitochondria, finally leading to exhaustion of the reserve respiratory capacity and cell death.
Topics & Concepts
IntracellularZebrafishSilver nanoparticleToxicityIonChemistryMitochondrionNanoparticleBiophysicsProgrammed cell deathCellEnvironmental chemistryNuclear chemistryNanotechnologyMaterials scienceBiochemistryBiologyApoptosisGeneOrganic chemistryNanoparticles: synthesis and applicationsHeavy Metal Exposure and ToxicityGraphene and Nanomaterials Applications