Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis
Ronald Jemmerson, Katherine Staskus, LeeAnn Higgins, Kathleen F. Conklin, Ameeta Kelekar
Topics & Concepts
ApoptosisTransfectionIntracellularCytochrome cBiologyInhibitor of apoptosis domainCell biologyCancer cellCytosolApoptosomeMolecular biologyProgrammed cell deathBiochemistryCaspaseGeneCancerEnzymeGeneticsClusterin in disease pathologyNuclear Structure and FunctionCell death mechanisms and regulation