Genome editing mRNA nanotherapies inhibit cervical cancer progression and regulate the immunosuppressive microenvironment for adoptive T-cell therapy
Kaijian Ling, Yin Dou, Neng Yang, Li Deng, Yanzhou Wang, Yudi Li, Leiyan Yang, Cheng Chen, Lupin Jiang, Qingchun Deng, Chenwen Li, Zhiqing Liang, Jianxiang Zhang
Topics & Concepts
Genome editingHeLaCRISPRCas9Tumor microenvironmentGenetic enhancementCancer researchImmunotherapyCD8ChemistryTransfectionGeneCancerBiologyComputational biologyMolecular biologyCellImmune systemImmunologyGeneticsBiochemistryTumor cellsVirus-based gene therapy researchRNA Interference and Gene DeliveryCRISPR and Genetic Engineering