Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis
Silvana Leit, Jeremy R. Greenwood, Sayan Mondal, Samantha Carriero, Markus K. Dahlgren, Geraldine Harriman, Joshua J. Kennedy‐Smith, Rosana Kapeller, Jon P. Lawson, Donna L. Romero, Angela V. Toms, Mee Shelley, Ronald T. Wester, William Westlin, Joshua McElwee, Wenyan Miao, Scott D. Edmondson, C. E. Masse
Topics & Concepts
Tyrosine kinase 2PsoriasisRheumatoid arthritisArthritisInterferonKinaseIn vivoChemistryPharmacologyImmunologyMedicineReceptorBiologyBiochemistryGeneticsGrowth factorPlatelet-derived growth factor receptorCytokine Signaling Pathways and InteractionsPsoriasis: Treatment and PathogenesisNF-κB Signaling Pathways