Heme induces inflammatory injury by directly binding to the complex of myeloid differentiation protein 2 and toll-like receptor 4
Jianjun Lin, Ke Lin, Lijiang Huang, Yongsheng Jiang, Xiaoxiao Ding, Wu Luo, А. В. Самородов, В. Н. Павлов, Guang Liang, Jianchang Qian, Yi Wang
Topics & Concepts
HemeInflammationTLR4Toll-like receptorProinflammatory cytokineCell biologyChemistrySignal transductionMAPK/ERK pathwayMyeloidReceptorInnate immune systemImmunologyBiologyBiochemistryEnzymeHeme Oxygenase-1 and Carbon MonoxideImmune Response and InflammationInflammasome and immune disorders