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Heme induces inflammatory injury by directly binding to the complex of myeloid differentiation protein 2 and toll-like receptor 4

Jianjun Lin, Ke Lin, Lijiang Huang, Yongsheng Jiang, Xiaoxiao Ding, Wu Luo, А. В. Самородов, В. Н. Павлов, Guang Liang, Jianchang Qian, Yi Wang

2022Toxicology Letters11 citationsDOI

Topics & Concepts

HemeInflammationTLR4Toll-like receptorProinflammatory cytokineCell biologyChemistrySignal transductionMAPK/ERK pathwayMyeloidReceptorInnate immune systemImmunologyBiologyBiochemistryEnzymeHeme Oxygenase-1 and Carbon MonoxideImmune Response and InflammationInflammasome and immune disorders
Heme induces inflammatory injury by directly binding to the complex of myeloid differentiation protein 2 and toll-like receptor 4 | Litcius