Protection against autoimmunity is driven by thymic epithelial cell–mediated regulation of T <sub>reg</sub> development
Claudia Haftmann, Pascale Zwicky, Florian Ingelfinger, Florian Mair, Stefan Floess, René Riedel, Pawel Durek, Marianne R. Spalinger, Ekaterina Friebel, Brian Leung, Mirjam Lutz, Nicole Puertas, Ana Amorim, Stefanie Schärli, Benedict Becher, Benedict Becher, Jan Kisielow, Ari Waisman, Mir‐Farzin Mashreghi, Jochen Huehn, Burkhard Becher, Burkhard Becher
Abstract
function, rather than negative selection, enforces the protection of peripheral tissues from autoimmune attack.
Topics & Concepts
AutoimmunityImmunologyBiologyCell biologyImmune systemImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses