Decoding cellular mechanism of recombinant adeno-associated virus (rAAV) and engineering host-cell factories toward intensified viral vector manufacturing
Yongdan Wang, Qiang Fu, So Young Park, Yong Suk Lee, Seo‐Young Park, Dong‐Yup Lee, Seongkyu Yoon
Topics & Concepts
BiologyPlasmidViral vectorViral replicationCapsidHEK 293 cellsVector (molecular biology)Gene deliveryCell biologyVirologyAdeno-associated virusVirusTransfectionRecombinant DNAComputational biologyGeneGeneticsVirus-based gene therapy researchCRISPR and Genetic EngineeringViral Infectious Diseases and Gene Expression in Insects