Photothermal theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient antibacterial treatment
Yuelan Wu, Xiaoxue Liu, Xiaoyu Zhang, Shuping Zhang, Panhong Niu, Hua Gao
Abstract
. Cytotoxicity and hemolysis analyses fully demonstrated the excellent biocompatibility of PDA-FDM-23. Overall, our work highlighted the strong peroxidase catalytic activity, excellent GSH consumption and photothermal performance of PDA-FDM-23, providing a new strategy for antibiotic-free reactive oxygen species (ROS) synergistic sterilization.
Topics & Concepts
Photothermal therapyGlutathioneReactive oxygen speciesChemistryAntibacterial activityOxygenBiophysicsNanotechnologyMaterials scienceBiochemistryBacteriaOrganic chemistryGeneticsEnzymeBiologyNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisAdvanced Photocatalysis Techniques