Effect of soluble oat fiber on intestinal microenvironment and TNBS-induced colitis
Seita Chudan, Riko Ishibashi, Miyu Nishikawa, Yoshiaki Tabuchi, Yoshinori Nagai, Shinichi Ikushiro, Yukihiro Furusawa
Abstract
Soluble oat fiber increased colonic butyrate, peripherally-induced Treg cells and thus alleviated TNBS-induced colitis, which coincided with overrepresentation of F. rodentium (a human analog of H. biformis ) possessing butyrate-producing metagenomes.
Topics & Concepts
ButyrateColitisChemistryFiberMicrobiologyPharmacologyBiochemistryBiologyImmunologyFermentationOrganic chemistryGut microbiota and healthDiet and metabolism studiesFood composition and properties