The Novel KLF4/BIG1 Regulates LPS-mediated Neuro-inflammation and Migration in BV2 Cells via PI3K/Akt/NF-kB Signaling Pathway
Zhijun You, Zhenzhen Yang, Shuang Cao, Shouheng Deng, Yi Chen
Topics & Concepts
Gene silencingPI3K/AKT/mTOR pathwayProtein kinase BCell biologyKLF4Gene knockdownChemistryMicrogliaSignal transductionInflammationBiologyCancer researchMolecular biologyCell cultureImmunologySOX2BiochemistryGeneticsGeneTranscription factorKruppel-like factors researchNeuroinflammation and Neurodegeneration MechanismsGenomics, phytochemicals, and oxidative stress