Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling
Yunxian Dong, Xiaoling Cao, Jinsheng Huang, Zhicheng Hu, Chufen Chen, Miao Chen, Long Qian, Zhongye Xu, Dongming Lv, Yanchao Rong, Sheng-Kang Luo, Haibin Wang, Wuguo Deng, Bing Tang
Topics & Concepts
MelatoninAutophagyPI3K/AKT/mTOR pathwayProtein kinase BLuzindoleFibroblastCell biologyEndocrinologyMelatonin receptorInternal medicineBiologyChemistryCancer researchSignal transductionApoptosisMedicineCell cultureBiochemistryGeneticsDermatologic Treatments and ResearchWound Healing and TreatmentsSkin Protection and Aging