Diarylheptanoid analogues from the rhizomes of<i>Zingiber officinale</i>and their anti-tumour activity
Ting Li, Dabo Pan, Qian‐Qian Pang, Mi Zhou, Xiaojun Yao, Xin‐Sheng Yao, Haibo Li, Yang Yu
Abstract
values ranging from 6.69-33.46 μM, and showed down-regulating the expression of ATR (ataxia telangiectasia mutated and RAD3-related) and CHK1 (checkpoint kinase 1) levels in HCT116 and A549 cell lines. Our studies not only enrich the structural diversity of diarylheptanoids in nature, but also discover several natural compounds for anti-tumor agents.
Topics & Concepts
Zingiber officinaleRhizomeTraditional medicineChemistryStereochemistryPharmacologyMedicineGinger and Zingiberaceae researchPharmacological Effects of Natural CompoundsZiziphus Jujuba Studies and Applications