Peripheral biomarkers' panel for severe COVID‐19 patients
Miriana d’Alessandro, Laura Bergantini, Paolo Cameli, Giuseppe Curatola, Lorenzo Remediani, Piersante Sestini, Elena Bargagli, Siena COVID Unit
Abstract
2] The authors propose an elevated CD4/CD8 ratio as a useful early predictive biomarker for development of critical illness in patients with COVID-19. Few weeks ago, we suggested natural killer (NK) cell count as a marker of severity in 34 hospitalized patients with COVID-19 but we did not observe any significant alterations in CD4-and CD8-lymphocyte counts or CD4/CD8 ratio. 7] is study aimed to investigate how a combination of COVID-19 severity markers could be helpful in the clinical management of these patients.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)VirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPeripheralMedicineSars virusBetacoronavirusInternal medicineDiseaseInfectious disease (medical specialty)OutbreakCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Immune Cell Function and Interaction