Anti-leukemia effects of omipalisib in acute myeloid leukemia: inhibition of PI3K/AKT/mTOR signaling and suppression of mitochondrial biogenesis
Chi-Yang Tseng, Yu-Hsuan Fu, Da‐Liang Ou, Jeng‐Wei Lu, Hsin‐An Hou, Liang‐In Lin
Topics & Concepts
PI3K/AKT/mTOR pathwayMyeloid leukemiaMitochondrial biogenesisProtein kinase BRPTORCancer researchBiologyLeukemiaMyeloidCell growthMitochondrionChemistrySignal transductionCell biologyBiochemistryImmunologyCancer, Hypoxia, and MetabolismHistone Deacetylase Inhibitors ResearchAcute Myeloid Leukemia Research