Epilepsy Occurrence and Circadian Rhythm: A Bibliometrics Study and Visualization Analysis via CiteSpace
Dongling Zhong, Shanxia Luo, Linli Zheng, Yonggang Zhang, Rongjiang Jin
Abstract
Objective To review the research status and demonstrate the hot spots and frontiers of epilepsy and circadian rhythm via CiteSpace. Method We searched Web of Science (WoS) for studies related to epilepsy and circadian rhythm from inception to 2020. CiteSpace was used to generate network maps about the collaborations between authors, countries, institutions and reveal hot spots and frontiers of epilepsy and circadian rhythm. Results A total of 704 studies related to epilepsy and circadian rhythm from the WoS were retrieved. Sanchez-Vazquez FJ was the most prolific author (17 articles). USA and University of Murcia were the leading country and institution in this field with 219 and 22 publications respectively. There were active collaborations among the authors, countries and institutions. Hot topics focused on the interaction between epilepsy and circadian rhythm, as well as possible novel treatments. Conclusions Based on the results of CiteSpace, the current study suggested active cooperation between authors, countries and institutions. Major ongoing research trends include the circadian rhythmicity of epilepsy based on different epileptic focus and the interaction between epilepsy and circadian rhythm, especially through melatonin, sleep–wake cycles and clock genes, which may implicate possible treatments (such as chronotherapy, neural stem cells transplantation) for epilepsy in the future.