Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
Susanne Gaul, Aleksandra Leszczynska, Fernando Alegre, Benedikt Kaufmann, Casey D. Johnson, Leon A. Adams, Alexander Wree, Georg Damm, Daniel Seehofer, Carolina Jiménez Calvente, Davide Povero, Tatiana Kisseleva, Akiko Eguchi, Matthew D. McGeough, Hal M. Hoffman, Pablo Pelegrı́n, Ulrich Laufs, Ariel E. Feldstein
Topics & Concepts
PyroptosisInflammasomeHepatic stellate cellHepatocyteLiver injuryFatty liverInflammationExtracellularFibrosisProgrammed cell deathCell biologyChemistryCancer researchBiologyImmunologyMedicinePathologyApoptosisBiochemistryEndocrinologyDiseaseIn vitroInflammasome and immune disordersLiver Disease Diagnosis and TreatmentLiver physiology and pathology