mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
Elodie Villa, Umakant Sahu, Brendan P. O’Hara, Eunüs S. Ali, Kathryn A. Helmin, John M. Asara, Peng Gao, Benjamin D. Singer, Issam Ben‐Sahra
Topics & Concepts
mTORC1BiologyProtein biosynthesisCell biologyRNAMessenger RNAMethionine AdenosyltransferaseTranslation (biology)Cell growthMethionineBiochemistrySignal transductionPI3K/AKT/mTOR pathwayGeneAmino acidRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation