Histone deacetylase 2 regulates STAT1-dependent upregulation of atypical chemokine receptor 3 to induce M2 macrophage migration and immune escape in hepatocellular carcinoma
Fu Chen, Liang Yang, Xueqiang Peng, Minghuan Mao, Xiaodan Liu, Jianbo Song, Jingyao Hu
Topics & Concepts
Downregulation and upregulationGene knockdownHistone deacetylase 2Cancer researchImmune systemIndoleamine 2,3-dioxygenaseChemokine receptorFOXP3ChemokineChemistryBiologyCell cultureHistone deacetylaseImmunologyHistoneBiochemistryAmino acidTryptophanGeneGeneticsHistone Deacetylase Inhibitors ResearchImmune cells in cancerEpigenetics and DNA Methylation