Inclusion of Dap10 or 4-1BB costimulation domains in the chPD1 receptor enhances anti-tumor efficacy of T cells in murine models of lymphoma and melanoma
Hailey Kintz, Emily Nylen, Amorette Barber
Topics & Concepts
CD28Chimeric antigen receptorCancer researchBiologyCytokineCancer immunotherapyReceptorImmunologyImmunotherapyT cellImmune systemBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses