Mitochondrial dynamics imbalance and mitochondrial dysfunction contribute to the molecular cardiotoxic effects of lenvatinib
Ayşenur Günaydın Akyıldız, Tuğçe Boran, Ayşe Tarbın Jannuzzi, Büket Alpertunga
Topics & Concepts
LenvatinibMFN1FIS1Mitochondrial fissionPharmacologyCardiotoxicitymitochondrial fusionAMPKChemistryCancer researchMitochondrionBiologyMedicineInternal medicineHepatocellular carcinomaKinaseToxicityCell biologyProtein kinase ABiochemistryMitochondrial DNASorafenibGeneChemotherapy-induced cardiotoxicity and mitigationGlutathione Transferases and PolymorphismsGenomics, phytochemicals, and oxidative stress