How Much is Enough? Impact of Efflux Transporters on Drug delivery Leading to Efficacy in the Treatment of Brain Tumors
Wenjuan Zhang, Ju‐Hee Oh, Wenqiu Zhang, Sneha Rathi, Jiayan Le, Surabhi Talele, Jann N. Sarkaria, William F. Elmquist
Topics & Concepts
EffluxDrugDrug deliveryPharmacologyBlood–brain barrierBrain tumorTransporterDistribution (mathematics)MedicineBiologyChemistryCentral nervous systemInternal medicinePathologyOrganic chemistryMathematicsMathematical analysisBiochemistryGeneGeneticsDrug Transport and Resistance MechanismsGlioma Diagnosis and TreatmentAmino Acid Enzymes and Metabolism