Ultrasmall porphyrin-silica core–shell dots for enhanced fluorescence imaging-guided cancer photodynamic therapy
Sadaf Hameed, Pravin Bhattarai, Zhuoran Gong, Xiaolong Liang, Xiuli Yue, Zhifei Dai
Abstract
study further revealed reduced tumor growth in 4T1 tumor-bearing bulb mice after laser irradiation explaining the excellent photodynamic therapeutic efficacy of ultra-small PSDs. Thus, ultrasmall hydrophilic PSDs combined with excellent imaging-guided therapeutic abilities and renal clearance behavior represent a promising platform for cancer imaging and therapy.
Topics & Concepts
Photodynamic therapyPorphyrinFluorescenceCore (optical fiber)Fluorescence-lifetime imaging microscopyMaterials scienceCancer therapyCancer imagingShell (structure)NanotechnologyPhotochemistryChemistryCancerMedicineOpticsPhysicsInternal medicineOrganic chemistryComposite materialNanoplatforms for cancer theranosticsAdvanced biosensing and bioanalysis techniquesPhotodynamic Therapy Research Studies