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Successful secukinumab treatment of active bullous pemphigoid and chronic severe psoriasis: a case report

Jenny Sung Won Yun, Laura Scardamaglia, Chin‐Guan Tan, Christopher McCormack

2022Australasian Journal of Dermatology22 citationsDOI

Abstract

Since the concurrence of bullous pemphigoid (BP) and psoriasis was first reported in 1929, an increasing number of studies has been published to analyse their relationship in recent years. However, the pathogenesis of the concurrence is not yet well understood, and the coexistence of the two conditions imposes a difficult therapeutic challenge. This case report demonstrates the first case of secukinumab achieving a dramatic clinical improvement of both chronic psoriasis and active BP.

Topics & Concepts

SecukinumabMedicineBullous pemphigoidDermatologyPsoriasisPlaque psoriasisPemphigoidImmunologyPsoriatic arthritisAntibodyAutoimmune Bullous Skin DiseasesUrticaria and Related ConditionsCoagulation, Bradykinin, Polyphosphates, and Angioedema