Elastase inhibitory activity of quinoline Analogues: Synthesis, kinetic mechanism, cytotoxicity, chemoinformatics and molecular docking studies
Balasaheb D. Vanjare, Young Seok Eom, Hussain Raza, Mubashir Hassan, Ki Hwan Lee, Song Ja Kim
Topics & Concepts
ChemistryCytotoxicityDocking (animal)QuinolineStereochemistryIC50ElastaseActive siteOleanolic acidEnzymeProton NMRMTT assayCarbon-13 NMRCoumarinMolecular modelCombinatorial chemistryBiochemistryIn vitroOrganic chemistryMedicinePathologyNursingAlternative medicineComputational Drug Discovery MethodsSynthesis and biological activityMetal complexes synthesis and properties