The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
Scott P. France, Russell D. Lewis, Carlos A. Martínez
Abstract
Biocatalysis is a highly valued enabling technology for pharmaceutical research and development as it can unlock synthetic routes to complex chiral motifs with unparalleled selectivity and efficiency. This perspective aims to review recent advances in the pharmaceutical implementation of biocatalysis across early and late-stage development with a focus on the implementation of processes for preparative-scale syntheses.
Topics & Concepts
BiocatalysisBiochemical engineeringNanotechnologyComputer scienceManagement scienceChemistryEngineeringMaterials scienceOrganic chemistryReaction mechanismCatalysisEnzyme Catalysis and ImmobilizationInnovative Microfluidic and Catalytic Techniques InnovationMicrobial Metabolic Engineering and Bioproduction