Recombinant SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Stimulate Release of Different Pro-Inflammatory Mediators via Activation of Distinct Receptors on Human Microglia Cells
Irene Tsilioni, Theoharis C. Theoharides
Topics & Concepts
NeuroinflammationMicrogliaReceptorRecombinant DNATLR4Cell biologyBiologyAngiotensin-converting enzyme 2ImmunologyInflammationNeuroscienceCoronavirus disease 2019 (COVID-19)MedicineBiochemistryInternal medicineGeneDiseaseInfectious disease (medical specialty)Long-Term Effects of COVID-19Neuroinflammation and Neurodegeneration MechanismsCOVID-19 Clinical Research Studies