Modular synthesis of unsymmetric 2,4-diaryl-substituted pyridines through a four-component cyclization strategy under metal-free conditions
Yanfeng Ma, Tianci Xu, Fuhong Xiao, Guojiang Mao, Guo‐Jun Deng
Abstract
We have reported a multicomponent protocol for the synthesis of polysubstituted pyridines through a [2 + 2 + 1 + 1] condensation sequence under metal-free conditions.
Topics & Concepts
ChemistryComponent (thermodynamics)Modular designCombinatorial chemistryProgramming languageComputer scienceThermodynamicsPhysicsCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsAsymmetric Synthesis and Catalysis