Ebola disease outbreak caused by the Sudan virus in Uganda, 2022: a descriptive epidemiological study
Zainah Kabami, Alex R. Ario, Julie R. Harris, Mackline Ninsiima, Sherry Rita Ahirirwe, Jane R. Aceng Ocero, Diana Atwine, Henry Mwebesa, Daniel Kyabayinze, Allan Muruta, Atek Kagirita, Yonas Tegegn, Miriam Nanyunja, Saudah N Kizito, Daniel Kadobera, Benon Kwesiga, Samuel Gidudu, Richard Migisha, Issa Makumbi, Daniel Eurien, Peter Elyanu, Alex Ndyabakira, Helen Nelly Naiga, Jane Frances Zalwango, Brian Agaba, Peter Chris Kawungezi, Marie Gorreti Zalwango, Patrick King, Brenda Nakafeero Simbwa, Rebecca Akunzirwe, Mercy Wendy Wanyana, Robert Zavuga, Thomas Kiggundu, Henry Kyobe Bosa, Allan Komakech, Doreen Nsiimire Gonahasa, Lilian Bulage, Irene Byakatonda Kyamwine, Denis Okethwangu, Joshua Kayiwa, Lisa J Nelson, Amy L Boore, Sandra Nabatanzi, Thomas Nsibambi, Jonathan Ntale, Christina Mwangi, Arthur G Fitzmaurice, Claire Biribawa, Enos Sande, Joseph Ojwang, Mary Choi, Terrence Lo, Jason Malefant, Trevor Shoemaker, Joel M Montgomery, Caitlin M Cossaboom, Carrie Eggers, John D Klena, Shannon Whitmer, Modupe O Osinubi, Katrin S Sadigh, Waverly Vosburgh, Mary-Claire Worrell, James A Fuller, Bernard Lubwama, Immaculate Nabukenya, Paul Edward Okello, Elizabeth Babirye Katana, Job Morukileng, Hildah Tendo Nansikombi, Paul Mbaka, Immaculate Atuhaire, Alice Asio, Sarah Elayeete, Edirisa Junior Nsubuga, Veronica Masanja, Stella Martha Migamba, Patience Mwine, Petranilla Nakamya, Rose Nampeera, Andrew Kwiringira, Mariam Komugisha, Brian Kibwika, Innocent Ssemanda, Yasiini Nuwamanya, Adams Kamukama, Dorothy Aanyu, Dominic Kizza, Shaban Senyange, Andrew Niwagaba Bakainaga, Godfrey Bwire, Felix Ocom, Milton Makoba Wetaka, Simon Kyazze, Anita Kisakye, Mohammed Lamorde, Lydia Nakiire, Peter Babigumira Ahabwe, Bernadette Basuta Mirembe, Esther Namukose Muwanguzi
Abstract
BACKGROUND: Uganda has had seven Ebola disease outbreaks, between 2000 and 2022. On Sept 20, 2022, the Ministry of Health declared a Sudan virus disease outbreak in Mubende District, Central Uganda. We describe the epidemiological characteristics and transmission dynamics. METHODS: ) estimates. FINDINGS: was 1·25. INTERPRETATION: . Children (aged <10 years) were at the highest risk of death, highlighting the need for targeted interventions to improve their outcomes during Ebola disease outbreaks. Initial care-seeking occurred at facilities outside the government system, showing a need to ensure that private and public facilities receive training to identify possible Ebola disease cases during an outbreak. Health-care-associated transmission in private health facilities drove the early outbreak, suggesting gaps in infection prevention and control. FUNDING: None.