Self-assembled nanoparticles based on cationic mono-/AIE tetra-nuclear Ir(<scp>iii</scp>) complexes: long wavelength absorption/near-infrared emission photosensitizers for photodynamic therapy
Ziwei Wang, Lijuan Li, Weijin Wang, Runlin Wang, Guangzhe Li, Hang Bian, Dongxia Zhu, Martin R. Bryce
Abstract
New cationic mono- and AIE tetra-nuclear Ir( iii ) complex-porphyrin conjugates and the corresponding carrier-free NP PSs by self-assembly methods without any auxiliary reagents, [TPP-Ir]+ NPs and [TPP-4Ir]4+ NPs, are obtained for highly efficient PDT.
Topics & Concepts
Photodynamic therapyPorphyrinAbsorption (acoustics)PhotochemistryBiocompatibilityChemistryCationic polymerizationNanoparticleCytotoxicityPhotosensitizerVisible spectrumMaterials scienceNanotechnologyOptoelectronicsIn vitroOrganic chemistryBiochemistryComposite materialNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPorphyrin and Phthalocyanine Chemistry