Targeting UHRF1-dependent DNA repair selectively sensitizes KRAS mutant lung cancer to chemotherapy
Danmei Tian, Jinshan Tang, Xinran Geng, Qingwen Li, Fangfang Wang, Huadong Zhao, Goutham Narla, Xin‐Sheng Yao, Youwei Zhang
Topics & Concepts
KRASLung cancerCancer researchBiologyChemotherapyCancerMutantMedicineInternal medicineBiochemistryGeneColorectal cancerGeneticsDNA Repair MechanismsRNA modifications and cancerUbiquitin and proteasome pathways