Phosphoinositide 3-kinase/Akt and its related signaling pathways in the regulation of tumor-associated macrophages polarization
Depeng Yang, Lijun Yang, Jialing Cai, Huaxin Li, Xing Zheng, Ying Hou
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayCancer researchTumor microenvironmentCell biologyChemokineMAPK/ERK pathwayPhosphoinositide 3-kinaseSignal transductionBiologyMacrophage polarizationImmune systemImmunologyPhenotypeBiochemistryGeneImmune cells in cancerPhagocytosis and Immune RegulationCancer Immunotherapy and Biomarkers