Staphylococcus lugdunensis: a Skin Commensal with Invasive Pathogenic Potential
Simon Heilbronner, Timothy J. Foster
Abstract
Staphylococcus lugdunensis is a species of coagulase-negative staphylococcus (CoNS) that causes serious infections in humans akin to those of S. aureus . It was often misidentified as S. aureus , but this has been rectified by recent routine use of matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) in diagnostic laboratories. It encodes a diverse array of virulence factors for adhesion, cytotoxicity, and innate immune evasion, but these are less diverse than those encoded by S. aureus .
Topics & Concepts
Staphylococcus lugdunensisStaphylococcus aureusMicrobiologyVirulenceBiologySortase AVirulence factorInnate immune systemImmunologyStaphylococcusImmune systemBacteriaGeneticsGeneAntimicrobial Resistance in StaphylococcusBiochemical and Structural CharacterizationBacterial biofilms and quorum sensing