Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke
Fengyang Li, Dan Xu, Kai Hou, Xue Gou, Ning Lv, Weirong Fang, Yunman Li
Topics & Concepts
PyroptosisPharmacologyClopidogrelInflammasomeMedicineTicagrelorReperfusion injuryIschemiaProinflammatory cytokineIn vivoAspirinChemistryInflammationImmunologyInternal medicineBiologyBiotechnologyInflammasome and immune disordersNeuroinflammation and Neurodegeneration MechanismsNeutrophil, Myeloperoxidase and Oxidative Mechanisms