Heparin-like anticoagulant polypeptides with tunable activity: Synthesis, characterization, anticoagulative properties and clot solubilities in vitro
Dedai Lu, Yuanyuan Jin, Xiangya Wang, Liyuan Xie, Qianqian Liu, Yamin Chen, Hui Wang, Ziqiang Lei
Topics & Concepts
Partial thromboplastin timeHeparinChemistryIn vitroThrombinAnticoagulantThrombin timePharmacologyPolymerizationCysteineStereochemistryBiochemistryCombinatorial chemistryMedicineCoagulationImmunologyPolymerSurgeryOrganic chemistryInternal medicinePlateletEnzymeProteoglycans and glycosaminoglycans researchPlatelet Disorders and TreatmentsProtease and Inhibitor Mechanisms