Litcius/Paper detail

The third-generation EGFR inhibitor almonertinib (HS-10296) resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs

Chung‐Pu Wu, Tai‐Ho Hung, Sabrina Lusvarghi, Yi-Hsuan Chu, Sung-Han Hsiao, Yang-Hui Huang, Yu‐Tzu Chang, Suresh V. Ambudkar

2021Biochemical Pharmacology40 citationsDOIOpen Access PDF

Topics & Concepts

Abcg2Multiple drug resistancePharmacologyT790MATP-binding cassette transporterCancer cellCancerEGFR inhibitorsTyrosine-kinase inhibitorDrug resistanceP-glycoproteinCancer researchMedicineEpidermal growth factor receptorBiologyTransporterInternal medicineGefitinibBiochemistryMicrobiologyGeneDrug Transport and Resistance MechanismsCancer therapeutics and mechanismsRadiopharmaceutical Chemistry and Applications