Dalbavancin
José Barberán, Alicia de la Cuerda, Lourdes Cristina Barberán
Abstract
Dalbavancin is a long-acting antimicrobial agent with an excellent in vitro activity against Gram-positive pathogens, including staphylococcal biofilms. The unusually long terminal half-life ranging from 149 to 250 hours in human subjects, allows a weekly dose. Currently is indicated in acute bacterial skin and skin structure infections (ABSSSIs), but in real-life clinical practice it has already been used successfully and safely in other infections, especially as consolidation therapy.
Topics & Concepts
DalbavancinAntimicrobialStaphylococcus aureusMedicineMicrobiologyBacteriaBiologyVancomycinGeneticsAntimicrobial Resistance in StaphylococcusDermatology and Skin DiseasesOcular Infections and Treatments