Litcius/Paper detail

The Development of Boron Analysis and Imaging in Boron Neutron Capture Therapy (BNCT)

Qi Dai, Qiyao Yang, Xiaoyan Bao, Jiejian Chen, Min Han, Qichun Wei

2022Molecular Pharmaceutics53 citationsDOI

Abstract

Boron neutron capture therapy (BNCT) is a selective biological targeted nuclide technique for cancer therapy. It has the following attractive features: good targeting, high effectiveness, and causes slight damage to surrounding healthy tissue compared with other traditional methods. It has been considered as one of the promising methods for the treatment of various cancers. Measuring 10B concentrations is vital for BNCT. However, the existing technology and equipment cannot satisfy the real-time and accurate measurement requirements, and more efficient methods are in demand. The development of methods and imaging applied in BNCT to help measure boron concentration is described in this review.

Topics & Concepts

Neutron captureBoronNuclideCancer therapyMedical physicsNeutron sourceRadiochemistryNuclear medicineCancerMaterials scienceMedicineNeutronChemistryPhysicsInternal medicineNuclear physicsOrganic chemistryBoron Compounds in ChemistryBoron and Carbon Nanomaterials ResearchRadiopharmaceutical Chemistry and Applications