Exploration of Benzo[b]carbazole-6,11-diones as anticancer agents: Synthesis and studies of hTopoIIα inhibition and apoptotic effects
Shailendra Sisodiya, Subarno Paul, Hiteshkumar Chaudhary, Preeti Grewal, G. Ravi Kumar, Divine P Daniel, Biswajit Das, Deepika Nayak, Sankar K. Guchhait, Chanakya Nath Kundu, Uttam Chand Banerjee
Topics & Concepts
ChemistryDAPICytotoxicityClonogenic assayApoptosisCancer cellCell cycleAnnexinEtoposideFlow cytometryCell cycle checkpointMTT assayAndrographolideCancer researchBiochemistryMolecular biologyCancerIn vitroBiologyChemotherapyGeneticsBioactive Compounds and Antitumor AgentsCancer therapeutics and mechanismsSynthesis and biological activity