Redox-sensitive carrier-free nanoparticles self-assembled by disulfide-linked paclitaxel-tetramethylpyrazine conjugate for combination cancer chemotherapy
Liang Zou, Xiaowei Liu, Jingjing Li, Wei Li, Lele Zhang, Chaomei Fu, Jinming Zhang, Zhongwei Gu
Abstract
results provide clear evidence that this redox-responsive carrier-free nanosystem with intrinsic amphiphilicity has great potential for combination cancer chemotherapy.
Topics & Concepts
PaclitaxelConjugateDisulfide bondChemistryRedoxChemotherapyNanoparticleCancer researchPharmacologyMedicineMaterials scienceNanotechnologyBiochemistryInternal medicineOrganic chemistryMathematicsMathematical analysisNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryAdvanced Nanomaterials in Catalysis