MicroRNA-22 promoted osteogenic differentiation of valvular interstitial cells by inhibiting CAB39 expression during aortic valve calcification
Fan Yang, Suxuan Liu, Ying Gu, Yan Yan, Xueyan Ding, Liang-jian Zou, Zhiyun Xu, Guokun Wang
Topics & Concepts
CalcificationRUNX2Aortic valvemicroRNACell biologyInterstitial cellBone morphogenetic protein 2ChemistryInternal medicineMedicineBiologyOsteoblastIn vitroBiochemistryGeneCardiac Valve Diseases and TreatmentsCancer-related molecular mechanisms researchMicroRNA in disease regulation