Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis
Stephanie Schwalm, Sandra Beyer, Redona Hafizi, Sandra Trautmann, Gerd Geißlinger, David R. Adams, Susan Pyne, Nigel J. Pyne, Liliana Schaefer, Andrea Huwiler, Josef Pfeilschifter
Topics & Concepts
Sphingosine kinase 1FibrosisSphingosineKinaseCancer researchMedicineBiologyPathologyCell biologySphingosine-1-phosphateReceptorInternal medicineSphingolipid Metabolism and SignalingEndoplasmic Reticulum Stress and DiseasePolysaccharides and Plant Cell Walls