Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering
Nicholas Marston, Frederick Kamanu, Giorgio Melloni, Gavin R. Schnitzler, Aaron Hakim, X. Rosa, Helen Kang, Daniel I. Chasman, Robert P. Giugliano, Patrick T. Ellinor, Paul M. Ridker, J Engreitz, Marc S. Sabatine, Christian T. Ruff, Rajat M. Gupta
Topics & Concepts
Internal medicineHazard ratioMedicineCohortSingle-nucleotide polymorphismRosuvastatinCoronary artery diseasePopulationStatinEndocrinologyCholesterolGastroenterologyBiologyGeneticsGenotypeConfidence intervalGeneEnvironmental healthLipoproteins and Cardiovascular HealthGenetic Associations and EpidemiologyAtherosclerosis and Cardiovascular Diseases