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Identification of Transient Intermediates and Active Species in Atomic CZA Catalysts for CO <sub>2</sub> Hydrogenation to Methanol

Leonardo da Silva Sousa, Andrea Bertuzzi, Tanna Elyn Rodrigues Fiuza, E. R. Leite, Patricia Benito, Davide Ferri, Daniela Zanchet, Andrew M. Beale

2025Journal of the American Chemical Society17 citationsDOIOpen Access PDF

Abstract

High Resolution Image Download MS PowerPoint Slide Direct hydrogenation of carbon dioxide to methanol is a promising strategy for carbon capture and utilization (CCU). Copper–zinc–alumina (CZA) catalysts are widely used for this transformation, yet the nature of the active Cu and Zn species and the reaction intermediates remains debated due to their sensitivity to feed composition and temperature. This challenge is compounded by the high metal loading in conventional CZA catalysts, which obscures active species signals with background contributions from spectator species. To address this, we synthesized model CuZn/Al 2 O 3 catalysts using bimetallic coordination complexes, achieving low metal loadings that yield small Cu clusters and Cu + single atoms adjacent to isolated Zn 2+ sites. In situ XANES and UV–vis data were analyzed using multivariate curve resolution–alternating least-squares (MCR–ALS), revealing that Cu dispersion and reagglomeration─phenomena suspected in industrial systems─also occur at low loadings. Operando and modulation excitation with phase sensitive detection DRIFTS (ME-PSD-DRIFTS) showed: (a) Cu clusters dissociate H 2 and activate CO 2 via monodentate formate; (b) Al 2 O 3 stabilizes Cu + under reducing conditions, with Cu content correlating with methanol productivity via CO hydrogenation; and (c) Zn in ZnAl 2 O 4 promotes CO 2 activation through reactive carbonate formation and enhances oxygenate conversion kinetics. ZnAl 2 O 4 also acts as a structural promoter, facilitating CO 2 conversion via reverse water gas shift (RWGS) and CO hydrogenation. These findings reveal new structure–activity relationships, highlighting the role of the mixed-metal interface in stabilizing transient intermediates and providing some guidance in the rational design of improved catalysts for CO 2 valorization.

Topics & Concepts

ChemistryBimetallic stripCatalysisMethanolOxygenateCarbon monoxideDispersion (optics)MetalReaction intermediateActive sitePhotochemistryInorganic chemistryDenticityHeterogeneous catalysisNanoparticleDecompositionYield (engineering)Ultrafast laser spectroscopyBifunctionalChemical engineeringActive centerCarbon fibersRational designChemical kineticsLayered double hydroxidesChemoselectivityCarbon dioxideWater-gas shift reactionCarbonateIn situPhase (matter)AdsorptionCatalysts for Methane ReformingCarbon dioxide utilization in catalysisCO2 Reduction Techniques and Catalysts
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