Challenges of Cell Counting in Cell Therapy Products
Muyun Liu, Wanglong Chu, Tao Guo, Xiuping Zeng, Yan Shangguan, Fangtao He, Liang Xiao
Abstract
Cell counting is a common and fundamental cell measurement technique that plays a crucial role in the development and quality control of cell therapy products. However, accurate and reliable cell counting can be challenging owing to the complexity of cell preparations, diverse counting purposes, and various counting methods. This review summarizes the challenges encountered in cell counting for cell therapy products and provides strategies to improve the cell counting accuracy, thereby guiding the counting process and ensuring the quality of cell therapy products.
Topics & Concepts
Cell countingCell therapyCellComputer scienceCounting processProcess (computing)Cell cycleChemistryMathematicsBiochemistryStatisticsOperating system3D Printing in Biomedical ResearchCell Image Analysis TechniquesCAR-T cell therapy research