Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury
Mariajose Metcalfe, Kelly Matsudaira Yee, Juan Luo, Jacob H. Martin-Thompson, Sunil Gandhi, Oswald Steward
Topics & Concepts
Spinal cordTransduction (biophysics)NeuroscienceAxonAxoplasmic transportPTENBiologyTransfectionTransgeneSpinal cord injurySignal transductionCell biologyGeneGeneticsPI3K/AKT/mTOR pathwayBiochemistryNerve injury and regenerationNeurogenetic and Muscular Disorders ResearchRNA Interference and Gene Delivery