POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis
Marta Llorens-Agost, Michael Ensminger, Hang Phuong Le, Anugrah Gawai, Jie Liu, Andrés Cruz-García, Sarita Bhetawal, Richard D. Wood, Wolf‐Dietrich Heyer, Markus Löbrich
Topics & Concepts
MitosisBiologyRAD52Cell biologyHomologous recombinationChromatinPolymeraseChromosome segregationGeneticsDNAMolecular biologyChromosomeRAD51GeneDNA Repair MechanismsPARP inhibition in cancer therapyCRISPR and Genetic Engineering