Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
Wei Li Adeline Koay, Sahera Dirajlal‐Fargo, Matthew E. Levy, Paige Kulie, Anne K. Monroe, Amanda D. Castel, Natella Rakhmanina, Lawrence J. D’Angelo, Natella Rakhmanina, Michael Kharfen, Michael Serlin, Princy Kumar, Aria Bamdad, Tsedenia Bezabeh, Pamela K. Burrows, Susan Reamer, Alla Sapozhnikova, Marinella Temprosa, Naji Younes, Morgan Byrne, Amanda D. Castel, Alan E. Greenberg, Maria Jaurretche, Matthew E. Levy, Anne K. Monroe, James Peterson, Lindsey Powers Happ, Brittany Wilbourn, Yan Ma, Hana Akselrod, Ronald D Wilcox, Sohail Rana, Michael A. Horberg, Ricardo Fernández, Annick Hebou, Carl W. Dieffenbach, Henry Masur, José Bordón, Gebeyehu Teferi, Debra Benator, Marı́a Elena Ruiz, Stephen Abbott
Abstract
Abstract We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01–.37]; P = .036) for a median follow-up of 527.5 days.