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Physical Activity and Nonalcoholic Fatty Liver Disease: A Roundtable Statement from the American College of Sports Medicine

Jonathan G. Stine, Michelle T. Long, Kathleen E. Corey, Robert E. Sallis, Alina M. Allen, Matthew J. Armstrong, David E. Conroy, Daniel J. Cuthbertson, Andrés Duarte‐Rojo, Kate Hallsworth, Ingrid J. Hickman, Matthew R. Kappus, Shelley E. Keating, Christopher J. A. Pugh, Yaron Rotman, TRACEY L. SIMON, Eduardo Vilar‐Gómez, Vincent Wai‐Sun Wong, Kathryn H. Schmitz

2023Medicine & Science in Sports & Exercise37 citationsDOIOpen Access PDF

Abstract

ABSTRACT: Although physical activity (PA) is crucial in the prevention and clinical management of nonalcoholic fatty liver disease, most individuals with this chronic disease are inactive and do not achieve recommended amounts of PA. There is a robust and consistent body of evidence highlighting the benefit of participating in regular PA, including a reduction in liver fat and improvement in body composition, cardiorespiratory fitness, vascular biology, and health-related quality of life. Importantly, the benefits of regular PA can be seen without clinically significant weight loss. At least 150 min of moderate or 75 min of vigorous intensity PA are recommended weekly for all patients with nonalcoholic fatty liver disease, including those with compensated cirrhosis. If a formal exercise training program is prescribed, aerobic exercise with the addition of resistance training is preferred. In this roundtable document, the benefits of PA are discussed, along with recommendations for 1) PA assessment and screening; 2) how best to advise, counsel, and prescribe regular PA; and 3) when to refer to an exercise specialist.

Topics & Concepts

Nonalcoholic fatty liver diseaseCardiorespiratory fitnessMedicineCirrhosisPhysical therapyChronic liver diseaseAerobic exerciseSports medicinePhysical activityLiver diseaseDiseaseInternal medicineFatty liverLiver Disease Diagnosis and TreatmentNutrition and Health in AgingMuscle metabolism and nutrition